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Information From Around The Globe

Marburg Research

During the summer of 2008, Marburg Research conducted a study on the effects of the United States Navy’s Utmb (Utility Tomographic Mapping) on the effectiveness of the US Navy’s aerial and ground-based surveillance system. The study found that Utmb is a very effective tool for improving the effectiveness of military communications, and is also highly useful for a variety of other applications. The study also determined that Utmb is a relatively inexpensive method for improving the effectiveness of military communications. The findings of this study are important to military planners and decision makers.

Methods

During the course of research for the Marburg virus, researchers have looked into many different aspects of the virus. The main focus of the research has been on defining the clinical significance of the virus and determining how to best protect humankind from the potentially deadly disease. Marburg virus has been identified as a priority pathogen by the World Health Organization (WHO), making it a serious public health threat. In addition to human to human transmission, the virus also spreads through contact with infected body fluids. It is also known to have mortality rates of up to 90% in humans.

Outcomes

UTMB scientists have made major progress in developing a vaccine against the deadly Marburg hemorrhagic fever virus. A new study published in the journal Nature Communications suggests that a vaccine containing two monoclonal antibodies and remdesivir may be effective against this virus, which is similar to Ebola. The researchers say their results could lead to a vaccine that could speed the response to an outbreak of Ebola in Africa.

The study is being carried out by researchers at UTMB’s Galveston National Laboratory, which is led by Professor Thomas Geisbert and Associate Professor Daniel Bornholdt. In this study, a Marburg-like virus was injected into mice. The infection resulted in an increase in virus titers in the mice’s intestines, uncontrolled viremia, and liver damage. Researchers found that the virus also causes thrombocytopenia and lymphopenia, which are hallmarks of Marburg hemorrhagic fever. In addition to these clinical symptoms, the mice also had liver damage similar to the pathology found in human NHPs.